Eliminating Defective Mitochondria

Here’s an interesting one:

https://actu.epfl.ch/news/targeting-an-rna-binding-protein-to-fight-aging/

It seems that an excess of PUM2 protein in cells causes a reduction of mitophagy, which eliminates defective mitochondria from cells. This then causes a lack of energy in old age which contributes to many of the problems of ageing. Removing that protein in old animals helps rejuvenate and extend lifespan.

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